Sedation Effects

Abstract

While respiratory concerns tend to be the first consideration with sedation medications, many can have important effects on the cardiovascular system that need to be managed. Changes in heart rate, blood pressure, and cardiac work have to be considered. While most of these medications will affect arterial blood pressure in one way or another, some will have no effect on heart rate. While one agent may work well in majority of patients, that same medication could have potentially devastating effects because of a patient’s underlying condition. Additionally, simply changing the rate of drug administration can potentially reduce or increase the cardiovascular effects.