Pharmacist’s Intervention on Pill Burden Effects on the Health-Related Quality of Life of Elderly Diabetic Patients in a Tertiary Hospital in Southwestern Nigeria

W. Ojieabu
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引用次数: 2

Abstract

Background: Diabetes and its associated complications take a toll on the elderly. It is known that medication burden could reduce patients’ adherence, which in turn impacts negatively on the health-related quality of life (HRQOL) of those suffering from chronic diseases. Studies have been conducted on HRQOL and its associated factors among diabetic patients but none has studied pill burden effects on HRQOL. This research evaluated pharmacist’s intervention on pill burden effects on the HRQOL of elderly diabetic patients. Methods: This 8-month randomized controlled study involved 170 elderly type 2 diabetic patients. Socio-demographics, the impact of the number and dosage frequency of drugs on adherence, and the influence of the pill burden on HRQOL scores were evaluated at baseline and at 4 and 8 months. Patients in the intervention group were educated about diabetes and its management and counselled on treatment adherence. Brisk walking was specially demonstrated to them at least 4 times during the study period. The control group received only the usual call reminders for appointment days. Results: At baseline, 58.8 and 64.7%, respectively, in the control and intervention groups responded “yes” (indicating a negative effect on their adherence) to >5 pills per prescription, while the figures were 55.3 and 15.3%, respectively, at 8 months (p = 0.711 and p = 0.000, respectively). Patients on 1–5 pills per prescription in the control group had the following physical functioning scores: baseline (44.2 ± 14.2) versus 4 months (47.2 ± 19.1) and 8 months (47.7 ± 16.1); p = 0.277 and p = 0.160. The physical functioning scores in the intervention group were: baseline (41.7 ± 16.1) versus 4 months (67.6 ± 23.1) and 8 months (92.5 ± 3.5); p ≤ 0.001. The same pattern of results was found for those on >5 pills per prescription. Conclusion: This study demonstrates pharmacists’ ability to improve the HRQOL of patients through continuous counselling, supply of relevant information, and monitoring of drug, exercise, and diet adherence. Intervention such as this could be beneficial to diabetic patients and others with chronic diseases.
药师干预药物负担对尼日利亚西南部某三级医院老年糖尿病患者健康相关生活质量的影响
背景:糖尿病及其相关并发症对老年人造成严重影响。众所周知,药物负担可能降低患者的依从性,这反过来又对慢性病患者的健康相关生活质量(HRQOL)产生负面影响。已有研究对糖尿病患者的HRQOL及其相关因素进行了研究,但没有研究药物负担对HRQOL的影响。本研究评价药师干预药物负担对老年糖尿病患者HRQOL的影响。方法:对170例老年2型糖尿病患者进行为期8个月的随机对照研究。在基线、4个月和8个月时评估社会人口统计学、药物数量和剂量频率对依从性的影响,以及药丸负担对HRQOL评分的影响。干预组的患者接受了有关糖尿病及其管理的教育,并接受了有关治疗依从性的咨询。在研究期间,专门向他们展示了至少4次快步走。对照组只收到预约日的常规电话提醒。结果:在基线时,对照组和干预组对每张处方>5片的回答分别为58.8%和64.7%(表明对其依从性有负面影响),而在8个月时,这一数字分别为55.3和15.3% (p = 0.711和p = 0.000)。对照组每处方1-5片患者的身体功能评分如下:基线(44.2±14.2),4个月(47.2±19.1)和8个月(47.7±16.1);P = 0.277和P = 0.160。干预组身体功能评分为:基线(41.7±16.1)、4个月(67.6±23.1)、8个月(92.5±3.5);P≤0.001。同样的结果也出现在那些每次服用5片以上药片的人身上。结论:本研究表明药师有能力通过持续的咨询、提供相关信息、监测药物、运动和饮食依从性来改善患者的HRQOL。这样的干预可能对糖尿病患者和其他慢性疾病患者有益。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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