Mathematical modelling of COVID-19 transmission and control strategies in the population of Bauchi State, Nigeria

Y. A. Misau, N. Nansak, A. Maigoro, S. Malami, D. Mogere, S. Mbaruk, R. Mohammed, S. Lawal, S. Usman
{"title":"Mathematical modelling of COVID-19 transmission and control strategies in the population of Bauchi State, Nigeria","authors":"Y. A. Misau, N. Nansak, A. Maigoro, S. Malami, D. Mogere, S. Mbaruk, R. Mohammed, S. Lawal, S. Usman","doi":"10.4081/aamr.2020.120","DOIUrl":null,"url":null,"abstract":"The novel SARS-COV-2 has since been declared a pandemic by the World Health Organization (WHO). The virus has spread from Wuhan city in China in December 2019 to no fewer than 200 countries as at June 2020 and still counting. Nigeria is currently experiencing a rapid spread of the virus amidst weak health system and more than 80% of population leaving on less than 1USD per day. To help understand the behavior of the virus in resource limited settings, we modelled the outbreak of COVID-19 and effects of control strategies in Bauchi state at north-eastern Nigeria. Using the real data of Bauchi state COVID-19 project, this research work extends the epidemic SEIR model by introducing new parameters based on the transmission dynamics of the novel COVID-19 pandemic and preventive measures. The total population of Bauchi State at the time of the study, given by is compartmentalized into five (5) different compartments as follows: Susceptible (S), Exposed (E), Infectious (I), Quarantined (Q) and Recovered (R). The new model is SEIQR. N = S → E → I → Q → R Data was collected by accessing Bauchi state electronic database of COVID-19 project to derive all the model parameters, while analysis and model building was done using Maple software. At the time of this study, it was found that the reproduction number R, for COVID-19 in Bauchi state, is 2.6 × 10-5. The reproduction number R decreased due to the application of control measures. The compartmental SEIRQ model in this study, which is a deterministic system of linear differential equations, has a continuum of disease-free equilibria, which is rigorously shown to be locallyasymptotically stable as the epidemiological threshold, known as the control reproduction number R= 0.0000026 is less than unity. The implication of this study is that the COVID-19 pandemic can be effectively controlled in Bauchi, since is R<1. Contact tracing and isolation must be increased as the models shows, the rise in infected class is a sign of high vulnerability of the population. Unless control measures are stepped up, despite high rate of recovery as shown by this study, infection rate will keep increasing as currently there is a no vaccine for COVID-19.","PeriodicalId":123248,"journal":{"name":"Annals of African Medical Research","volume":"57 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2020-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of African Medical Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4081/aamr.2020.120","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2

Abstract

The novel SARS-COV-2 has since been declared a pandemic by the World Health Organization (WHO). The virus has spread from Wuhan city in China in December 2019 to no fewer than 200 countries as at June 2020 and still counting. Nigeria is currently experiencing a rapid spread of the virus amidst weak health system and more than 80% of population leaving on less than 1USD per day. To help understand the behavior of the virus in resource limited settings, we modelled the outbreak of COVID-19 and effects of control strategies in Bauchi state at north-eastern Nigeria. Using the real data of Bauchi state COVID-19 project, this research work extends the epidemic SEIR model by introducing new parameters based on the transmission dynamics of the novel COVID-19 pandemic and preventive measures. The total population of Bauchi State at the time of the study, given by is compartmentalized into five (5) different compartments as follows: Susceptible (S), Exposed (E), Infectious (I), Quarantined (Q) and Recovered (R). The new model is SEIQR. N = S → E → I → Q → R Data was collected by accessing Bauchi state electronic database of COVID-19 project to derive all the model parameters, while analysis and model building was done using Maple software. At the time of this study, it was found that the reproduction number R, for COVID-19 in Bauchi state, is 2.6 × 10-5. The reproduction number R decreased due to the application of control measures. The compartmental SEIRQ model in this study, which is a deterministic system of linear differential equations, has a continuum of disease-free equilibria, which is rigorously shown to be locallyasymptotically stable as the epidemiological threshold, known as the control reproduction number R= 0.0000026 is less than unity. The implication of this study is that the COVID-19 pandemic can be effectively controlled in Bauchi, since is R<1. Contact tracing and isolation must be increased as the models shows, the rise in infected class is a sign of high vulnerability of the population. Unless control measures are stepped up, despite high rate of recovery as shown by this study, infection rate will keep increasing as currently there is a no vaccine for COVID-19.
尼日利亚包奇州人口中COVID-19传播的数学模型和控制策略
此后,世界卫生组织(WHO)宣布新型SARS-COV-2为大流行。截至2020年6月,该病毒已从2019年12月的中国武汉市传播到不少于200个国家,并且仍在增加。尼日利亚目前正在经历病毒的迅速传播,卫生系统薄弱,80%以上的人口每天生活费不足1美元。为了帮助了解病毒在资源有限的情况下的行为,我们模拟了尼日利亚东北部包奇州COVID-19的爆发和控制策略的效果。本研究利用包奇州COVID-19项目的真实数据,基于新型COVID-19大流行的传播动态和预防措施,引入新的参数,扩展了流行病SEIR模型。在研究时,包奇州的总人口被划分为五(5)个不同的区室,如下:易感(S),暴露(E),感染(I),隔离(Q)和恢复(R)。新的模型是SEIQR。N = S→E→I→Q→R通过访问包奇州COVID-19项目电子数据库收集数据,导出所有模型参数,并使用Maple软件进行分析和模型构建。在本研究时,发现包奇州COVID-19的繁殖数R为2.6 × 10-5。由于采取了控制措施,繁殖数R下降。本研究的区室SEIRQ模型是一个线性微分方程的确定性系统,具有连续的无病平衡,当流行病学阈值(即控制繁殖数R= 0.0000026)小于1时,严格证明该模型是局部渐近稳定的。本研究提示包奇市COVID-19大流行可以得到有效控制,R<1。必须加强接触者追踪和隔离,正如模型所显示的那样,受感染人群的增加是人口高度脆弱性的标志。如果不加强控制措施,尽管该研究显示出很高的恢复率,但由于目前没有针对COVID-19的疫苗,感染率将继续上升。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信