Successful use of octreotide and limited drainage in resistant chylothorax in congenital diaphragmatic hernia

Rajendran Ramaswamy, K. Gopala, Saif Galib, S. Hegab
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Abstract

In the conservative treatment of postdiaphragmatic hernia chylothorax, use of octreotide (OCT) had variable results. Limited chyle drainage has not been tried. A newborn, after the left Bochdalek diaphragmatic hernia repair, developed chylothorax. Treatment with intercostal chest tube (ICT) drainage, partial parenteral nutrition (PPN), and medium-chain triglyceride (MCT) with formula feeds was ineffective. ICT slipped out on the 13th day in the presence of significant residual chylothorax. Further drainage was not done. Addition of OCT infusion at maximum dose of 6 μg/kg/h cleared the chylothorax. No side effect of OCT was observed. The present case has proved that MCT feeding along with PPN is effective, and limited drainage of chyle is enough with OCT treatment in postdiaphragmatic hernia chylothorax.
奥曲肽联合有限引流治疗先天性膈疝顽固性乳糜胸的成功应用
在膈后疝乳糜胸的保守治疗中,奥曲肽(OCT)的使用有不同的结果。有限的乳糜引流尚未尝试。新生儿左膈疝修补术后发生乳糜胸。肋间胸管(ICT)引流、部分肠外营养(PPN)和中链甘油三酯(MCT)配合配方饲料治疗无效。在乳糜胸明显残留的情况下,ICT于第13天滑出。没有进一步引流。添加最大剂量6 μg/kg/h的OCT对乳糜胸有清除作用。OCT未见副作用。本病例证明MCT喂养联合PPN治疗膈后疝乳糜胸的OCT治疗是有效的,有限的乳糜引流是足够的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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