Have the number of pulmonary embolism cases increased during the COVID-19 pandemic?

Emine Afşin, Emine Özsarı, Suat Konuk, Derya Kocadağ, Emre Bacaksiz
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Abstract

Background. Coagulation disorders, endothelial dysfunction, immobility and dehydration contribute to deep vein throm-bosis (DVT) and pulmonary embolism (PE) in COVID-19 patients. While the prevalence of PE accompanying COVID-19 is high, the number of studies on its long-term effects is limited in literature. Objectives. We expanded this process and aimed to evaluate a one-year period before and during the pandemic. We sought an answer to the question: "Is there a change in the frequency and clinical course of PE?" Material and methods. Retrospectively, all patients admitted to our pulmonology clinic diagnosed with PE between October 2018-2019 (pre-pandemic) and April 2020-2021 (pandemic period) were included in the study. PE patients hospitalized due to COVID-19 infection were not included in the study. Results. The prevalence of PE cases increased by 43% in the first year of the pandemic, and there was no significant difference in terms of symptoms, localisation and extent of thrombus in the pulmonary artery, DVT frequency, systolic pulmonary artery pressure (PABs) values, right heart load, frequency of thrombolytic therapy and mortality rates. A significant decrease was observed in predisposing factors of pulmonary embolism only in the postoperative period (7 patients (77.8%) before the pandemic;2 patients (22.2%) during the pandemic;p = 0.029). Conclusions. PE cases are encountered more frequently during the pandemic process, and no significant change was seen in patient's clinical findings and mortality.
在2019冠状病毒病大流行期间,肺栓塞病例数量是否有所增加?
背景。凝血功能障碍、内皮功能障碍、不活动和脱水导致COVID-19患者深静脉血栓形成(DVT)和肺栓塞(PE)。虽然伴随新冠肺炎的PE患病率很高,但文献中关于其长期影响的研究数量有限。目标。我们扩大了这一进程,旨在对大流行之前和期间的一年时间进行评估。我们寻求这个问题的答案:“PE的频率和临床病程是否有变化?”材料和方法。回顾性研究纳入了2018年10月至2019年10月(大流行前)和2020年4月至2021年4月(大流行期)期间在肺科诊所确诊为PE的所有患者。因COVID-19感染住院的PE患者未纳入研究。结果。在大流行的第一年,PE病例的患病率增加了43%,在症状、肺动脉血栓的位置和程度、DVT频率、肺动脉收缩压(PABs)值、右心负荷、溶栓治疗频率和死亡率方面没有显著差异。仅在术后期间观察到肺栓塞的易感因素显著减少(大流行前7例(77.8%);大流行期间2例(22.2%);p = 0.029)。结论。PE病例在大流行过程中更为常见,患者的临床表现和死亡率没有明显变化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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