A family with hereditary intracerebral cavernous angiomas.

Abstract

There are a very few reports in literature of inherited intracerebral cavernous angiomas. The majority of them are Mexican-American families. In some of the reported families autosomal dominant transmission is suggested. We report a family in which three members of three consecutive generations were proven to have multiple intracerebral cavernous malformations, without involvement of skin, eyes, or other viscera. An autosomal dominant mode of inheritance is clearly suggested.