Analysis of factors impacting Sarcopenia in geriatric patients through the use of data sciences: A Case Study in Tijuana, Mexico

Verónica Rojas-Mendizabal, C. Castillo-Olea, Jocelyn Gomez Siono, C. Zuniga
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Abstract

Sarcopenia is the loss of muscle mass associated with the ageing process. Moreover, it is a progressive disease affecting older people. In 2017, about 12 million mexican elder people suffered from Sarcopenia; nevertheless, many of them are not aware of their condition. A study conducted by the Instituto Mexicano del Seguro Social (IMSS) estimates that 72.10% of people with Sarcopenia were women, while the rest were men [1]. This study analyses a database which includes the information of 166 geriatric patients from Tijuana, Baja California state. The database encompasses 90 variables, including biomedical information and some demographic information such as age, gender, address, schooling, marital status, level of education, income, profession, and financial support. An analysis to find the weight factors that impact the development of sarcopenia was carried out by generating a decision tree using the database provided by the General Hospital of Tijuana and the support of Orange software. Based on the creation of this tree, the relation and impact of the most important factors was analyzed. Among the three most important risk factors for this disease, besides senescence, the results from the analysis showed that Major Neurocognitive Disorder (MND), Systolic Arterial Hypertension (SAH), and malnutrition are the most important conditions to consider. These obtained results were compared with results retrieved from a study where the analysis was done through a Python simulation using machine learning methods with the same database.
通过使用数据科学分析影响老年患者肌肉减少症的因素:墨西哥蒂华纳的案例研究
肌肉减少症是与衰老过程相关的肌肉质量损失。此外,这是一种影响老年人的进行性疾病。2017年,约有1200万墨西哥老年人患有肌肉减少症;然而,他们中的许多人并没有意识到自己的状况。墨西哥社会研究所(Instituto Mexicano del Seguro Social, IMSS)的一项研究估计,72.10%的肌肉减少症患者为女性,其余为男性[1]。本研究分析了一个数据库,其中包括来自下加利福尼亚州蒂华纳的166名老年患者的信息。该数据库包含90个变量,包括生物医学信息和一些人口统计信息,如年龄、性别、地址、学校教育、婚姻状况、教育水平、收入、职业和财政支持。利用Tijuana总医院提供的数据库和Orange软件的支持,通过生成决策树,对影响肌肉减少症发展的体重因素进行了分析。在建立该树的基础上,分析了各重要因素之间的关系和影响。在本病的三个最重要的危险因素中,除衰老外,分析结果显示,主要神经认知障碍(MND)、收缩期动脉高血压(SAH)和营养不良是最需要考虑的因素。将这些获得的结果与从一项研究中检索到的结果进行比较,该研究通过使用具有相同数据库的机器学习方法的Python模拟进行分析。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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