Two cases of pyogenic liver abscess due to Klebsiella pneumoniae in immunocompetent children

Abstract

Pyogenic liver abscess (PLA) is not a common disease in children, with an incidence of 10/100,000 hospitalizations. In children with PLA, Staphylococcus aureus is the most common pathogenic organism. Recently, there has been an increasing incidence of PLA due to Klebsiella pneumoniae in Korea. This disease entity has been found to be caused by one of the following: bacteria entering portal circulation; primary bacteremia; and cryptogenic infection. Although the improved diagnostic modalities and antibiotic therapy have decreased mortality, PLA remains a fatal disease with mortality rates ranging from 8.2% to 16.8%. Immunocompromising diseases, such as chronic granulomatous diseases, diabetes mellitus or malignancy, and preexisting hepatobiliary or pancreatic diseases predispose children to PLA. Despite such risk factors, we recently experienced 2 immunocompetent children with PLA. In this case report, we report the 2 cases of successfully treated PLA due to K. pneumoniae in the children. 건강한 소아에서 발생한 폐렴막대균에 의한 간농양 2례