Helicobacter Pylori is the Cause of Gastric Cancer

Abstract

Objective: This study presents a systematic meta-analysis of the relationship between Helicobacter pylori (HP) infection and gastric cancer (GC). Materials and Methods: Twelve articles including 21589 subjects were selected (1237 cases and 20352 controls). These data were analyzed using the mathematical formula of the conditio sine qua non relationship and the causal relationship formula. Results: The data re-analyzed support the Null hypothesis without a Helicobacter pylori infection no human gastric cancer. The causal relationship between HP and GC is highly significant. Conclusion: Helicobacter pylori is the cause of human gastric cancer.