{"title":"Finding optimal control policy by using dynamic programming in conjunction with state reduction","authors":"X. Chen, W. Ching","doi":"10.1109/ISB.2011.6033165","DOIUrl":null,"url":null,"abstract":"In this paper we study the problem of finding optimal control policy for probabilistic Boolean networks (PBNs). Previous works have been done by using dynamic programming-based (DP) method. However, due to the high computational complexity of PBNs, DP method is computationally inefficient for large networks. Inspired by the state reduction strategies studied in [10], we consider using dynamic programming in conjunction with state reduction approach to reduce the computational cost of DP method. Numerical examples are given to demonstrate the efficiency of our proposed method.","PeriodicalId":355056,"journal":{"name":"2011 IEEE International Conference on Systems Biology (ISB)","volume":"22 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2011-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"5","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"2011 IEEE International Conference on Systems Biology (ISB)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/ISB.2011.6033165","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 5
Abstract
In this paper we study the problem of finding optimal control policy for probabilistic Boolean networks (PBNs). Previous works have been done by using dynamic programming-based (DP) method. However, due to the high computational complexity of PBNs, DP method is computationally inefficient for large networks. Inspired by the state reduction strategies studied in [10], we consider using dynamic programming in conjunction with state reduction approach to reduce the computational cost of DP method. Numerical examples are given to demonstrate the efficiency of our proposed method.