Partial orchiectomy: Experience of four cases in a secondary hospital of greece

J. Kyriazis, D. Dimitriou, M. Karavitakis, A. Thanos
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Abstract

Aim of the Study: The aim of this study is to review our collective experience with partial orchectomy due to testicular tumors in a secondary hospital of Greece. Materials and Methods: In total four young patients with relative indications for a partial orchectomy (single testis and/or tumors <2 cm in diameter, patient consent for a close follow-up, negative tumor markers) underwent partial orchiectomy in our institution. All operations were performed under clamping of the spermatic cord, and postoperative period was uneventful. Results: Pathology examination revealed one case of Sertoli cell only tumor, one patient with testicular cancer of mixed pathology (embryonal and teratoma), one case of organized hematoma, and one case with focal atypical inflammation. Patients underwent a close follow-up protocol. The patient with the mixed tumor was subjected to adjuvant chemotherapy with BEP (bleomycin, etoposide, cisplatin). The patient with atypical inflammation had a single testis due to a history of contralateral seminoma. During follow-up, he developed local tumor recurrence and underwent orchiectomy that revealed the presence of seminoma. The patient was set under testosterone replacement therapy. Conclusions: Partial orchiectomy represents a safe treatment option in the management of small testicular tumors. A benign pathology in up to 50% of cases should be expected. In case of both malignant and benign pathologies, a close follow-up is deemed necessary for the timely recognition of local recurrences in case of insufficient cancer eradication.
希腊某二级医院睾丸部分切除术4例临床分析
研究目的:本研究的目的是回顾我们在希腊一家二级医院因睾丸肿瘤而进行部分睾丸切除术的集体经验。材料和方法:共有4例年轻患者接受了部分睾丸切除术(单个睾丸和/或肿瘤直径< 2cm,患者同意密切随访,肿瘤标志物阴性)。所有手术均在精索夹持下进行,术后无意外。结果:病理检查显示仅支持细胞肿瘤1例,混合病理(胚胎性和畸胎瘤)睾丸癌1例,组织性血肿1例,局灶性非典型炎症1例。患者接受了密切的随访方案。混合肿瘤患者行BEP(博来霉素、依托泊苷、顺铂)辅助化疗。由于对侧精原细胞瘤病史,非典型炎症患者有单睾丸。随访期间,局部肿瘤复发,行睾丸切除术,发现存在精原细胞瘤。患者接受睾酮替代疗法。结论:睾丸部分切除术是治疗小睾丸肿瘤的一种安全的治疗选择。良性病理在高达50%的病例应该预期。对于恶性和良性病变,密切的随访是必要的,以便在根除癌症不足的情况下及时发现局部复发。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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