Large-scale computational microscopy

Abstract

This talk will describe computational imaging methods for fast capture of gigapixel-scale 3D intensity and phase images in a commercial microscope. Our experimental setups employ illumination-side and detection-side coding of angle (Fourier) space with simple hardware and fast acquisition. The result is high-resolution reconstructions across a large field-of-view, achieving high space-bandwith-time product. Experimentally, we achieve real-time 3D and phase imaging with digital aberration correction and mitigation of scattering effects, by sparsity-constrained nonlinear optimization methods.