[Analysis of interactions between influenza virus and murine serum proteins in non-infected and infected mice].

Abstract

The presence of proteins in the blood of intact mice of various lines which could form complexes of various stability with influenza virus and have antigen determinants common with mouse IgG was demonstrated. These proteins were different from mouse IgG and their molecular weight was 100-200 and 40-80 kD. The authors described quantitative changes in the studied proteins during simulated influenza as well as under the effect of ionol (antioxidant) administration. The study permitted the assumption that blood serum proteins of intact mice participate in the infection progression and are significant for its prognosis.