Evidence based on patient’s experience data and clinical guidelines-for patient-oriented clinical decision support

Congqian Wu, Liang Xiao
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Abstract

In view of the fact that evidence-based clinical decision support systems (CDSS) mostly make objective decisions based on clinical evidence, ignoring the subjective preferences of patients. How to provide the most suitable and personalized medical plan for a particular patient is a problem that should be considered at present. For this purpose, we propose to use patients’ experience data and clinical guidelines as knowledge sources to construct evidence in order to support patient-oriented clinical decision-making. In this paper, we propose a side-effect knowledge model, which can model the side-effect knowledge obtained from two data sources: patient experience data and clinical guidelines to support mining patient preferences in a more fine-grained form. In addition, we also propose a comprehensive decision-making system architecture that can consider both the patient’s clinical symptoms and subjective preferences, so as to provide more comprehensive and interpretable decision support for clinicians and patients. We designed and implemented a prototype system to prove the feasibility of this decision support system architecture.
基于患者经验数据和临床指南的证据-以患者为导向的临床决策支持
鉴于循证临床决策支持系统(CDSS)多基于临床证据进行客观决策,忽略了患者的主观偏好。如何为特定患者提供最合适、最个性化的医疗方案,是当前需要考虑的问题。为此,我们建议将患者的经验数据和临床指南作为知识来源,构建证据,以支持以患者为导向的临床决策。在本文中,我们提出了一个副作用知识模型,该模型可以对从患者经验数据和临床指南两个数据源获得的副作用知识进行建模,以支持以更细粒度的形式挖掘患者偏好。此外,我们还提出了一种综合考虑患者临床症状和主观偏好的决策系统架构,为临床医生和患者提供更全面、可解释的决策支持。我们设计并实现了一个原型系统,以证明该决策支持系统架构的可行性。
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