An Algorithm for stable Microtubule Curvature Conformation

Abstract

Self-assembly is a ubiquitous, naturally occurring, robust process in many living organisms. Microtubule, a self-organization system assembles itself into functional units by attaching to cellular structures. Modeling microtubule self-organization is of interest as microtubule forms a network of protein filaments that is critical to many processes in eukaryotic cells. In this paper, we developed a modeling algorithm starting from alpha and beta tubulins as basic building block in the self-organization of microtubule. The developed algorithm and the necessary steps are described in detail. The preliminary results obtained from the model demonstrate that a stable self-organization conformation is possible for a microtubule.