Integration of enzyme immobilised single-walled carbon nanotube arrays into microfluidic devices for glucose detection

Abstract

Microfluidic devices for glucose detection have been constructed and developed by integration of glucose oxidase covalently immobilised single-walled carbon nanotube arrays into a poly (dimethylsiloxane)-based microfluidic channel. This microfluidic device was tested for electrochemical glucose detection, and the results showed that the glucose can be detected with a linear response up to a concentration of 5times10-3 mol L-1. Because of the small amounts of fluids and enzyme used in microchannels, this approach offers a number of technical advantages, such as portability, shorter analysis time and lower consumption of expensive analytes.