Fiber-Based Speckle Contrast Optical Tomography for Neuroimaging in Humans: Simulation of High-Density vs. Sparse Arrays and In Vivo Human Measurements

Abstract

We simulated speckle contrast optical tomography performance based on an anatomical head model comparing sparse and high-density arrays. We also demonstrated measurements of pulsatile flow on a human head using a multi-mode fiber-based speckle system.