Efficacy and safety of Chinese Herbal Medicine for Vascular dementia: A protocol of systematic review and meta-analysis

Medicine: Case Reports and Study Protocols Pub Date : 2022-01-18 DOI:10.37766/inplasy2022.1.0098

Aihua Tan, Yan Hu, Han Yan, Zheng-zheng Zhang, Ziyu Song, Simiao Ran

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Abstract

Review question / Objective: As a common type of clinical dementia, the prevalence rate of vascular dementia(VaD) increased rapidly in recent years, damaging both patients’ health and social-economic prospect. There is currently no effective treatment for VaD, though western medicines can slightly improve patients' cognitive function, but not brought a significant improvement in daily life ability. Chinese herbal medicine(CHM) has been widely employed to treat dementia for more than 2000 years in China. Despite the proliferation of relevant literature, there is still a lack of evidence to prove the effectiveness and safety of such therapy. Therefore, this systematic review and meta-analysis protocol is aimed to assess the efficacy and safety of CHM forVaD. Information sources: 6 English databases (PubMed, Web of Science, Embase, Springer, CENTRAL and WHO International Clinical Trials Registry Platform) and 4 Chinese databases (Wan fang Database, Chinese Scientific Journals Database, China National Knowledge Infrastructure Database and Chinese Biomedical Literature Database).

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中药治疗血管性痴呆的疗效和安全性:一项系统评价和荟萃分析方案

综述问题/目的:血管性痴呆(VaD)作为一种常见的临床痴呆类型，近年来患病率迅速上升，给患者的健康和社会经济前景造成了损害。VaD目前没有有效的治疗方法，西药虽能轻微改善患者的认知功能，但并没有带来日常生活能力的显著改善。在中国，中草药被广泛用于治疗痴呆症已有2000多年的历史。尽管相关文献大量涌现，但仍缺乏证据证明该疗法的有效性和安全性。因此，本系统综述和荟萃分析方案旨在评估CHM治疗vad的有效性和安全性。信息来源:6个英文数据库(PubMed、Web of Science、Embase、Springer、CENTRAL和WHO国际临床试验注册平台)和4个中文数据库(万方数据库、中国科学期刊数据库、中国国家知识基础数据库和中国生物医学文献数据库)。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Medicine: Case Reports and Study Protocols

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