[Bacteriology of abdominal pus in 43 cases of acute appendicitis and appendiceal abscess at the Ivrea-Castellamonte Hospital, isolation of aerobic and anaerobic bacteria and drug sensitivity].

C Guasco, F Ronchetto, P Milani, E Stacchini, P G Pistono
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Abstract

A retrospective study on the microbiology of abdominal pus from acute appendicitis or peritonitis was carried out by the authors. A total of 45 specimens were examined, 38 of them (84.4%) where found to be positive, of which 29 (76.3%) were polymicrobial and 9 (23.7%) were monomicrobial. The most represented species were Escherichia coli (28.4%), Bacteroides fragilis (7.8%), Streptococcus milleri (7.8%), Bacteroides oralis (3.9%) and Pseudomonas aeruginosa (3.9%). The polymicrobial associations more represented include Bacteroidaceae, Enterobacteriaceae and streptococcus genus. The most active drugs in vitro were found to be Piperacillin and Chloramphenicol, Cephalosporin (cefotaxime, ceftriaxone and cefoxitin) showed a good capability of being active against isolated microorganisms although they were less effective when used against anaerobic microorganisms then aerobic ones. On the contrary, Rifampicin, Metronidazole and Clindamycin were found to be quite effective against the anaerobes.

【Ivrea-Castellamonte医院43例急性阑尾炎及阑尾脓肿腹部脓液细菌学分析、好氧、厌氧菌分离及药敏分析】。
回顾性研究急性阑尾炎或腹膜炎腹腔脓液的微生物学。共检测标本45份,阳性38份(84.4%),其中多微生物29份(76.3%),单微生物9份(23.7%)。以大肠杆菌(28.4%)、脆弱拟杆菌(7.8%)、milleri链球菌(7.8%)、口腔拟杆菌(3.9%)和铜绿假单胞菌(3.9%)为代表。较有代表性的多微生物关联包括拟杆菌科、肠杆菌科和链球菌属。体外活性最高的药物是哌拉西林和氯霉素,头孢菌素(头孢噻肟、头孢曲松和头孢西丁)对分离的微生物具有良好的活性,但对厌氧微生物的活性低于好氧微生物。相反,利福平、甲硝唑和克林霉素对厌氧菌很有效。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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