Diagnostics of non-equilibrium atmosperic plasma jets for cancer therapy

M. Keidar
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Abstract

Summary form only given. Plasma medicine is a relatively new field that outgrew from research in application of low-temperature (or cold) non-equilibrium atmospheric plasmas in bioengineering. One of the most promising applications of cold atmospheric plasma (CAP) is the cancer therapy. Convincing evidence of CAP selectivity towards the cancel cells has been accumulated. This presentation will review recent research efforts in developing various diagnostics of non-equilibrium atmospheric plasma jets. In particular, we will focus on kHz frequency range discharges. Variety of experimental diagnostic approaches was developed including Rayleigh microwave scattering, Thomson laser scattering, electrostatic streamer scatterers, optical emission spectroscopy, and fast imaging. We will address phenomena related to atmospheric nonequilibrium jets including ionization mechanism, process of ionization front propagation, electrical coupling of the ionization front with the discharge electrodes, distributions of excited and ionized species etc. In general, it was found that there is good electric conductivity of the streamer channel and electrodes potential is transferred to the streamer tip without significant potential. Air content in the helium flow governs streamer propagation along the straight path, its cross-sectional structure, and maximal streamer length. Excitation of the streamer with low frequency high voltage is associated with the streamer initiation at the moment when minimal breakdown conditions are reached.
非平衡大气等离子体射流诊断癌症治疗
只提供摘要形式。等离子体医学是低温(或冷)非平衡大气等离子体在生物工程中的应用研究发展起来的一个相对较新的领域。低温大气等离子体(CAP)最有前途的应用之一是癌症治疗。已经积累了令人信服的CAP对取消细胞选择性的证据。本报告将回顾最近在发展各种非平衡大气等离子体射流诊断方面的研究成果。特别是,我们将重点放在千赫频率范围内的放电。开发了多种实验诊断方法,包括瑞利微波散射、汤姆逊激光散射、静电飘流散射、光学发射光谱和快速成像。我们将讨论与大气非平衡射流有关的现象,包括电离机理、电离锋传播过程、电离锋与放电电极的电耦合、激发态和电离态的分布等。总的来说,我们发现流道具有良好的导电性,电极电位传递到流道尖端没有明显的电位。氦气流中的空气含量决定了流光沿直线路径的传播、流光的横截面结构和最大流光长度。在达到最小击穿条件的时刻,低频高压对流子的激励与流子的起始有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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