Therapeutic role of Omega-3 fatty acids in improving PCOS and PCOS related complications

Tabeen Irfan, B. Rizwan, Kinza Seher, M. Aslam, S. Bashir
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Abstract

To our insight, despite a few preliminaries investigating the helpful impact of n-3 polyunsaturated unsaturated fats (PUFA) on polycystic ovary disorder (PCOS), not many studies are done to examine the impacts of n-3 PUFA utilization on PCOS inconveniences. In this manner, our point was to write a review to explore the potential impact of omega 3 and related components. An extensive, precise search was led in Embase, MEDLINE/PubMed, Google Scholar, and SCOPUS to recognize n-3 unsaturated fats are helpful for improving PCOS complications. In this review, the effect of omega-3 on PCOS, mechanism of omega 3, omega-3 and insulin obstruction, omega-3 and adipokines, omega-3 and lipid metabolism, omega-3 and endothelial capacity, and omega-3 and hormonal elements are mentioned. There are various systems by which n-3 PUFAs might apply their valuable consequences for PCOS, including weight loss, glycemic and hormonal hemostasis, mitigating, the guideline of adipokine creation, and improvement of endothelial capacity. N-3 PUFAs are promising in easing inconveniences related to PCOS. The majority of the examinations in patients with PCOS showed an improvement in many Pcos related complications by the use of omega-3. Also, positive impacts regarding the improvement of dyslipidemia, guideline of adipokines, guideline of hormonal elements, and upgrade of endothelial capacity are restricted. Accordingly, more preliminaries are justified to examine attractive instruments for explaining the metabolic and hormonal impacts of these specialists in PCOS.
Omega-3脂肪酸在改善PCOS及PCOS相关并发症中的治疗作用
据我们所知,尽管对n-3多不饱和不饱和脂肪(PUFA)对多囊卵巢疾病(PCOS)的有益影响进行了一些初步研究,但对n-3 PUFA利用对PCOS不便的影响的研究并不多。通过这种方式,我们的目的是写一篇综述,探讨omega - 3和相关成分的潜在影响。在Embase、MEDLINE/PubMed、Google Scholar和SCOPUS中进行了广泛而精确的搜索,以确认n-3不饱和脂肪有助于改善PCOS并发症。本文就omega-3对PCOS的影响、机制、omega-3与胰岛素阻塞、omega-3与脂肪因子、omega-3与脂质代谢、omega-3与内皮功能、omega-3与激素成分等进行综述。n-3 PUFAs可能在多种系统中应用其对多囊卵巢综合征的有价值的影响,包括减肥,血糖和激素止血,缓解,指导脂肪因子的产生,以及改善内皮细胞的能力。N-3 PUFAs有望缓解与PCOS相关的不便。大多数多囊卵巢综合征患者的检查显示,使用omega-3可改善许多与多囊卵巢综合征相关的并发症。此外,在改善血脂异常、调节脂肪因子、调节激素因子、提高内皮细胞容量等方面的积极作用也受到限制。因此,更多的初步研究是合理的,以检查有吸引力的仪器来解释这些多囊卵巢综合征专家的代谢和激素影响。
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