Der Einfluß des intravesikalen Volumens auf die Blasenantwort unter sakraler Vorderwurzelstimulation vor und nach Blasenüberdehnung

Abstract

The influence of intravesical volume on bladder response during sacral anterior root stimulation (SARS) was investigated in animal experiments. Following lum bal laminectomy in 9 male foxhounds, bilateral placement of the sacral anterior roots S2 and S3 into a modified Brindley electrode was performed. The bladder was filled in 50 ml steps in the first series up to 700 ml and in the second series up to 300 ml. At these different intravesical volumes, the bladder was stimulated by sacral neurostimulation and intravesical pressure was measured and registered. In all dogs, intravesical pressure during Stimulation was influenced by the intravesical volume. Maximum increase in intravesical pressure (69.1 cm H 2 O) was observed at an average intravesical volume of 100 ml. With increasing intra vesical volume after this maximum, the increased pressure slowly dropped down to 11.2 cm H 2 O at 700 ml. After overdisten sion, an average reduction in intravesical pressure of 19% in relation to the initial pressure was observed. Therefore, overdisten sion should be prevented in patients with disturbed bladder function because of the reduction in bladder response during and after overdistension.