Flow Measurement in Stented Left Coronary Artery Models

Kensuke Ono, K. Yamamoto, T. Tsukahara, M. Motosuke, H. Kawamoto, S. Tahara, Kentaro Tanaka, S. Nakamura
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Abstract

Ischemic heart disease, a generic term for angina pectoris and myocardial infarction, is caused by blood flow failure due to a lesion generated in the coronary artery of the heart. Because the ischemic heart disease causes fatal problems, a stent placement technique called the percutaneous coronary intervention (PCI) is frequently performed to expand coarctated arteries to recover the function. However, although the PCI technique is a less-invasive technique, there is a risk of complications such as stent thrombosis and restenosis due to the placed stent. In order to understand the cause and the mechanism of the complications, effects of the stent placement and the stent shape on the blood flow is experimentally investigated. Silicone left coronary artery models were prepared to perform particle tracking velocimetry (PTV) and calculated the wall shear stress (WSS). The measurement results show that the flow structure and the WSS are changed depending on the deformation of the stent and the location of the placed stent.
左冠状动脉支架模型的血流测量
缺血性心脏病是心绞痛和心肌梗死的总称,是由于心脏冠状动脉病变导致血流衰竭而引起的。由于缺血性心脏病会导致致命的问题,一种被称为经皮冠状动脉介入治疗(PCI)的支架置入技术经常被用于扩张缩窄的动脉以恢复其功能。然而,尽管PCI技术是一种侵入性较小的技术,但由于放置支架,存在支架血栓形成和再狭窄等并发症的风险。为了了解并发症的原因和机制,我们实验研究了支架放置和支架形状对血流的影响。制备硅胶左冠状动脉模型,进行颗粒跟踪测速(PTV)并计算壁剪应力(WSS)。测量结果表明,支架的变形和放置支架的位置会改变支架的流动结构和WSS。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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