Design of 1.0V O2 and H2O2 based Potentiostat

Abstract

In this paper, a unified potentiostat which can measure the current of both O2-based and H2O2-based blood glucose sensors with low supply voltage of 1.0V has been designed and verified by simulations and measurements. Potentiostat is composed of low-voltage operational transconductance amplifier, cascode current mirrors and mode-selection circuits. It can measure currents of blood glucose chemical reactions occurred by O2 or H2O2. The body of PMOS input differentional stage of the operational transconductance amplifier is forward-biased to reduce the threshold voltage for low supply voltage operation. Also, cascode current mirror is used to reduce current measurement error generated by channel length modulation effects. The proposed low-voltage potentiostat is designed and simulated using Cadence SPECTRE and fabricated in Magnachip 0.18um CMOS technology with chip size of 110μm×60μm. The measurement results show that consumption current is maximum 46μA at supply voltage of 1.0V. Using the persian potassium(K3Fe(CN)6) equivalent to glucose, the operation of the fabricated potentiostat was confirmed. 키워드 : 정전압분극장치, 혈당측정센서, 연산 트랜스컨덕턴스 증폭기, 캐스코드 전류거울 Key word : Potentiostat, Glucose Sensor, Operational Transconductance Amplifier, Cascode Current Mirror Received 04 October 2016, Revised 24 October 2016, Accepted 30 October 2016 * Corresponding Author Yeong-Seuk Kim(E-mail:kimys@cbnu.ac.kr Tel:+82-43-261-3137) Department of Semiconductor Engineering, Chungbuk National University, Cheongju 28644, Korea Open Access http://doi.org/10.6109/jkiice.2017.21.2.345 print ISSN: 2234-4772 online ISSN: 2288-4165 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License(http://creativecommons.org/li-censes/ by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Copyright C The Korea Institute of Information and Communication Engineering. Journal of the Korea Institute of Information and Communication Engineering 한국정보통신학회논문지(J. Korea Inst. Inf. Commun. Eng.) Vol. 21, No. 2 : 345~352 Feb. 2017