[Studies on the cell and tissue tolerance of a polymeric bone replacement material].

Abstract

BOP (Biocompatible Osteoconductive Polymer) shows no cytotoxicity in vitro. After six months of subcutaneous implantation in mice a weak cellular tissue reaction is seen histologically. The hard tissue reaction after six months of implantation in fractured tibia bone shows less connective tissue between the implant material BOP and bone.