Design and fabrication of cell adhesion measuring device

Abstract

Cell adhesion phenomena has an important role on different behavior of cell. Therefore qualitative and quantitative understanding of cell adhesion force is necessary. A low cost micro device has been developed that can demonstrate cell adhesion force against a specific mechanical stimuli. The device that we developed here allows the measuring cell adhesion. This device is made based on poly methyl methacrylate (PMMA). Finally, to test the system functions, we obtained viscoelastic parameters of cell by applying 10 micron displacement that had a good agreement with literature.