[Etiopathogenesis of periapical lesions].

Abstract

In recent years, considerable interest has been generated in the role of bacteria in causing periapical pathogenesis. This article reviews and correlates clinical and laboratory research bearing on this important topic. Bacteria in dental root canals play a decisive role in the development of periapical lesions and some of them have the ability to establish themselves in periapical tissue. Multiple mechanisms are involved: they include also immunological responses.