False-positive symptoms of recurrence of gastroesophageal reflux disease (gerd) in patients with hiatal hernia (hh) after anti-reflux videolaparoscopy

V. Oskretkov, E. A. Tseimakh, A. Andreasyan, M. Grigoryan, S. Maslikova
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Abstract

We compared the results of remote survey of 213 patients with HH associated with GERD in the long term after anti-reflux videolaparoscopy, according to the GERD-HRQL, GIQLI, and SF-36 questionnaires (patients’ complaints) and special methods for studying the anti-reflux function of the cardia (X-ray endoscopy of the esophagus and stomach, daily esophageal pH monitoring, esophageal manometry). Based on the results of special studies, a generalized indicator of failure of the anti-reflux function of the cardia (GIFAFC) was developed. It was found that 57.3% of the examined patients had false-positive symptoms of GERD recurrence, which was manifested by pain in the epigastric region (31.2%), belching with air (4.1%), and heartburn (21.3%). There were no symptoms when bent over or lying down. The existing symptoms were mild, easily stopped by conservative treatment. The patients with false-positive GERD symptoms after surgery showed an improvement in GIFAFC by 7.9 times (p <0.001), but it was 5.4 times worse than in patients without recurrent GERD (p <0.001), and 6.3 times better in relation to patients with recurrent GERD (p<0.05). False-positive symptoms of GERD recurrence contributed to a decrease in the generalized indicator of quality of life, which, according to the SF-36 questionnaire, was 76% of the maximum desired result. Due to the absence of reliable clinical manifestations, all patients with HH who have certain symptoms of GERD after fundoplication should undergo an instrumental study of the anti-reflux function of the cardia. Patients with established false-positive symptoms of GERD are subject to dispensary follow-up.
裂孔疝(hh)患者在抗反流腹腔镜检查后胃食管反流病(gerd)复发的假阳性症状
我们根据GERD- hrql、GIQLI、SF-36问卷(患者主诉)和研究心脏抗反流功能的特殊方法(食道和胃x线内窥镜、每日食道pH监测、食道测压),对213例抗反流视频腹腔镜术后长期伴有胃食管反流的HH患者远程调查结果进行比较。基于专门研究的结果,提出了一种通用的心脏抗反流功能失效指标(GIFAFC)。结果发现,57.3%的被检查患者有GERD复发的假阳性症状,表现为上腹部疼痛(31.2%)、嗳气(4.1%)和胃灼热(21.3%)。弯腰或躺下时没有症状。现有症状较轻,经保守治疗即可痊愈。假阳性GERD患者术后GIFAFC改善7.9倍(p< 0.001),但比无复发GERD患者差5.4倍(p< 0.001),比复发GERD患者好6.3倍(p<0.05)。GERD复发的假阳性症状导致广义生活质量指标下降,根据SF-36问卷,该指标为最大期望结果的76%。由于缺乏可靠的临床表现,所有HH患者在复底后有一定的GERD症状,都应进行心脏抗反流功能的仪器研究。确诊为胃食管反流假阳性症状的患者需接受药房随访。
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