PROBLEMS OF EARLY DIAGNOSIS OF CHEMOTHERAPY-INDUCED PERIPHERAL NEUROPATHY

Abstract

Chemotherapy-induced peripheral neuropathy (CIPN) is a progressive, long-lasting and often irreversible condition characterized by pain, numbness, tingling, and sensitization to cold in the hands and feet that affects 30 to 40% of patients undergoing chemotherapy. This leads to disability and a deterioration in the quality of life of patients against the background of the absence of tumor progression, representing a serious side effect of treatment. There are certain clinical risk factors for CIPN, but none of them accurately indicates the severity and possibility of developing the disease in oncologic patients. Prediction, early detection and monitoring of side effects of chemotherapy is of great importance in the treatment of cancer patients. Further research in this field will make it possible to correctly and effectively plan and carry out treatment and rehabilitation arrangements using preventive technologies.