[Advances in the treatment of the dystonias].

Archivos de neurobiologia Pub Date : 1991-09-01
S Giménez-Roldán
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Abstract

Except in Wilson's disease, few secondary dystonias are susceptible to benefit from an aetiological treatment. The somatic distribution of dystonia often determines the therapeutic strategy. Thus, stereotactic surgery may be the treatment of choice for hemidystonia while anticholinergic medication may alleviate generalized dystonia, particularly in childhood. Finally, local infiltrations of botulinum toxin are particularly useful for various forms of local and segmental dystonia. Certain subsyndromes as myoclonic dystonia, levodopa sensitive dystonia and paroxysmal choreoathetosis may benefit from relatively specific treatment strategies.

肌张力障碍的治疗进展。
除威尔逊氏病外,很少继发性肌张力障碍容易从病因治疗中获益。肌张力障碍的躯体分布往往决定了治疗策略。因此,立体定向手术可能是半肌张力障碍的治疗选择,而抗胆碱能药物可能减轻全身性肌张力障碍,特别是在儿童时期。最后,肉毒杆菌毒素的局部浸润对各种形式的局部和节段性肌张力障碍特别有用。某些亚综合征如肌阵挛性肌张力障碍、左旋多巴敏感性肌张力障碍和阵发性舞蹈症可能受益于相对特定的治疗策略。
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