Hereditary mucinous ovarian cancer complicated with omental metastasis: A case report

A. Das
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Abstract

Approximately 80% ovarian tumorsare benign, and these arise mostly in young adult females. Malignant tumors are more prevalent in ageing women, between the ages of 45-65 years. Mucinous ovarian cancer represents about 5% of epithelial ovarian cancers (EOC).We have reported a case of mucinous cystadenocarcinoma in 35-year-old lady with metastasis to omentum.Imaging (radiograph & CT scan) studies showed a large right sided pelvic mass with probable origin in the right ovary. Cancer antigen-125 was elevated, while carcinoembrionic antigen and alphafetoprotein were normal. Mutational profiles shown distinct finding, as KRAS mutations positive nevertheless p53 and BRCA mutations are absent. She had undergone total abdominal hysterectomy with bilateral salphingo-oopher-ectomy along with pelvic dissection for removal of lymph nodes at the age of 35. She was given advice for radiotherapy with 3 cycles of che-motherapy with cisplatin and paclitaxel. To the best of our knowledge, this is the one of the littlecase of ovarian mucinous cystadenocarcinoma being reported at a relatively young age, and the first case being reported from Bangladesh.
遗传性黏液性卵巢癌合并大网膜转移1例
大约80%的卵巢肿瘤是良性的,这些肿瘤大多发生在年轻的成年女性。恶性肿瘤在年龄在45-65岁之间的老年妇女中更为普遍。粘液性卵巢癌约占上皮性卵巢癌(EOC)的5%。我们报告一例35岁女性粘液囊腺癌伴大网膜转移。影像学(x线片和CT扫描)显示右侧盆腔肿块大,可能起源于右侧卵巢。癌抗原125升高,癌胚抗原、甲胎蛋白正常。突变谱显示出明显的发现,KRAS突变阳性,而p53和BRCA突变不存在。她在35岁时接受了全腹子宫切除术和双侧salphingo-oopher切除术以及骨盆清扫术以切除淋巴结。建议行顺铂和紫杉醇联合放疗3个周期。据我们所知,这是在相对年轻的年龄报道的少数卵巢粘液囊腺癌病例之一,也是孟加拉国报道的第一例。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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