Incidence, Risk Factors and Immediate Outcome of Preterm Neonates: A Hospital Based Study

N. Acharya, S. Poudel
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Abstract

Introduction: Preterm birth is defined as birth before 37 completed weeks of gestation. It is one of the leading cause of infant morbidity and mortality in the world. Aims: The study was aimed to find out the incidence, possible risk factors and outcome of inborn preterm babies till they were discharged from the hospital. Methods: This is a prospective hospital based study. A total of 100 preterm babies delivered in Nepalgunj Medical College Teaching Hospital, Kohalpur and admitted in Neonatal Intensive Care Unit (NICU) were studied. Preterms were divided into 2 groups extremely to very preterm (<32 weeks) and moderate to late preterm (≥ 32 weeks). The preterm babies were evaluated for various morbidities sand mortality till they were discharged from the hospital. Results: Data of 100 babies was analyzed. Out of 100 preterm babies 40 were extremely to very preterm babies (<32 weeks) and 60 were moderate to late preterm babies (≥32 weeks).  Significant risk factors associated with preterm deliveries were inadequate antenatal visits (73%), primi gravidity (58%), preterm premature rupture of membrane (55%), urinary tract infection (54%), anemia (53%), teenage pregnancy (43%), antepartum hemorrhage (41%) and pregnancy induced hypertension (33%). The total mortality was higher in extremely to late preterm than in moderate to late preterm. The most common causes of mortality were Neonatal sepsis (NNS), Hyaline Membrane Disease (HMD) and Birth Asphyxia. Conclusion: The hospital incidence of preterm neonates is still very high. The major risk factor seen in the study was inadequate antenatal visit. Preventive measures, early identification of risk factors will improve the outcome.
早产新生儿的发生率、危险因素和直接结局:一项基于医院的研究
前言:早产的定义是在妊娠37周之前出生。它是世界上婴儿发病和死亡的主要原因之一。目的:本研究旨在了解早产儿在出院前的发生率、可能的危险因素及转归。方法:这是一项基于医院的前瞻性研究。本文对100名在科哈尔布尔尼泊尔医学院附属医院分娩并入住新生儿重症监护病房(NICU)的早产儿进行研究。将早产儿分为极早产儿至极早产儿(<32周)和中度早产儿至晚期早产儿(≥32周)两组。对早产儿的各种发病率和死亡率进行评估,直到他们出院。结果:对100例婴儿的数据进行分析。在100例早产儿中,40例为极早产儿至极早产儿(<32周),60例为中度至晚期早产儿(≥32周)。与早产相关的重要危险因素是产前检查不足(73%)、初产(58%)、早产胎膜早破(55%)、尿路感染(54%)、贫血(53%)、少女怀孕(43%)、产前出血(41%)和妊高征(33%)。重度至晚期早产儿的总死亡率高于中度至晚期早产儿。最常见的死亡原因是新生儿脓毒症(NNS)、透明膜病(HMD)和出生窒息。结论:早产儿在医院的发病率仍然很高。研究中发现的主要风险因素是产前检查不足。预防措施,早期识别风险因素将改善结果。
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