Smoking Tobacco – a Risk Factor for Breast Cancer

Marta Szkiela, E. Kusideł, Ewa Siwińska-Beck, T. Makowiec-Dąbrowska
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Abstract

Abstract Introduction In 2009, the International Agency for Research on Cancer (IARC) stated that there was “limited evidence of a cause and effect relationship between an increased risk of breast cancer and smoking”. Environmental tobacco smoke is known to cause cancer by exerting both carcinogenic and genotoxic effects. The aim of the study was to assess the relationship between smoking (active and passive) and breast cancer risk. Material and methods The case/control study was conducted from 2015– –2019 in the Lodz region. The case group included 384 women with breast cancer; the control group included 298 healthy women. The research tool was an anonymous questionnaire. Results In the group of 682 respondents, 63% have ever smoked cigarettes (65.4%/60.1% in the case/control group respectively), 22.1% were current smokers, 67% were exposed to passive smoking. In the majority of cases, women were exposed to smoking by the husband (86%), the father (55.5%) or both (43.2%). Breast cancer risk is 253–271% higher for smokers (current – past) in comparison to the group of non-smokers, never exposed to passive smoking. The risk for passive smokers is 139% higher than for those not exposed. Conclusions Exposure to environmental tobacco smoke increases the risk of breast cancer. Public awareness of the negative consequences of passive smoking should be raised.
吸烟是乳腺癌的一个危险因素
2009年,国际癌症研究机构(IARC)表示,“有限的证据表明,乳腺癌风险增加与吸烟之间存在因果关系”。众所周知,环境烟草烟雾通过发挥致癌和基因毒性作用而导致癌症。这项研究的目的是评估吸烟(主动和被动)与乳腺癌风险之间的关系。材料与方法病例/对照研究于2015 - 2019年在罗兹地区进行。病例组包括384名患有乳腺癌的女性;对照组包括298名健康女性。研究工具是一份匿名问卷。结果682名被调查者中,有吸烟史的占63%(65.4%/60.1%),目前吸烟者占22.1%,有被动吸烟暴露者占67%。在大多数情况下,妇女吸烟是由丈夫(86%)、父亲(55.5%)或两者(43.2%)造成的。与从未被动吸烟的非吸烟者相比,吸烟者(现在和过去)患乳腺癌的风险高253-271%。被动吸烟者的风险比未接触者高139%。结论接触环境中的烟草烟雾会增加患乳腺癌的风险。应提高公众对被动吸烟负面后果的认识。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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