Phytochemical Screening and Antioxidant Activity of Leaves and Stem Bark Extracts of Garcinia Imberti - An Endangered Plant

Dr. Rajkumar Kandhasamy, Shubharani Ramnath, Sivaram Venkataramegowda
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引用次数: 5

Abstract

Garcinia imberti Bourd. a critically endangered tree belongs to the family Clusiaceae found only in India. The phytochemicals and antioxidant studies were carried out for the methanolic extracts of Garcinia imberti leaves and stem bark using DPPH and ABTS radical scavenging assay. Preliminary phytochemical screening of methanolic extracts of Garcinia imberti revealed the presence of various bioactive components like alkaloids, flavanoids, steroids, glycosides, phenols, saponins, terpenoids, resins, carbohydrates and tannins in both leaves and stem bark. The quantitative analysis of phytochemicals of the extracts showed the presence of high amount of tannins (0.92 ± 0.23mg/gm) and alkaloids (0.83 ± 0.48mg/gm) in leaf and high concentration of flavanoids (0.65±0.16mg/gm) and tannins (0.78±1.12mg/gm) in bark extract. The result of the present study concluded that the methanolic extracts of Garcinia imberti leaves and stem bark possess antioxidant activity due to the presence of significant amount of phenolic compounds which are the major contributors of antioxidant activity. The finding of this study suggests that the studied plant is a potential source of natural antioxidant that could have great importance as therapeutic agents in preventing or slowing the progress of oxidative stress related degenerative diseases.
濒危植物藤黄叶、茎皮提取物的植物化学筛选及抗氧化活性研究
Garcinia imberti Bourd。一种极度濒危的树,只在印度发现。采用DPPH法和ABTS自由基清除法对黄芩叶和茎皮甲醇提取物的化学成分和抗氧化性进行了研究。初步的植物化学筛选表明,黄酮类、甾体、苷类、酚类、皂苷类、萜类、树脂、碳水化合物和单宁等多种生物活性成分均存在于黄酮类和黄酮类化合物的叶和茎皮中。植物化学成分定量分析表明,叶中单宁含量高(0.92±0.23mg/gm),生物碱含量高(0.83±0.48mg/gm),树皮提取物中黄酮类含量高(0.65±0.16mg/gm),单宁含量高(0.78±1.12mg/gm)。结果表明,黄芩叶和茎皮的甲醇提取物具有抗氧化活性,其主要成分为酚类化合物。本研究的发现表明,所研究的植物是天然抗氧化剂的潜在来源,可能在预防或减缓氧化应激相关退行性疾病的进展中具有重要的治疗作用。
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