[HLA antigens in patients with osteoarticular tuberculosis and chronic hematogenic osteomyelitis].

Abstract

There have been examined 93 patients with the tuberculosis of bones and joints, 28 patients with chronic hematogenic osteomyelitis. All patients have been typed in accordance with the antigens of loci HLA-A, B, C and DR by means of standard microlymphocytotoxic test. 135 healthy donors have been typed according to the same loci++ HLA as controls (105 persons have been typed according to antigens of locus HLA-DR). All examined persons have been Uzbeks. There have been stated that in the patients with the tuberculosis of bones and joints, as compared with osteomyelitis, is observed the increase of frequency of antigens HLA-B27 and HLA-DR2, while in case of bone osteomyelitis is noted association with antigens HLA-A9, B7 and B18.