Rhinocerebral Mycosis: Combined Modality Protocol

Abstract

Rhinocerebral mycosis is an invasive fungal infection which occurs primarily in the paranasal sinuses and progresses to involve the brain and/or the orbit. It is commonly seen in immunocompromised individuals and can be most effectively treated if diagnosed early, when it is limited to the nasal cavity and the paranasal sinuses. Even though it is acceptable that surgical debridement in combination with antifungal therapy can lead to high rate of cure, the surgical approach for intracranial extension is still a subject of debate. Twenty-four cases of rhinocerebral mycosis managed at our institute are discussed, regarding presenting complaints and management.