[The dynamics of the cerebral circulation and of brain functional activity in patients with initial atherosclerotic encephalopathy under the influence of a single intravenous administration of sermion].

Farmakologiia i toksikologiia Pub Date : 1991-07-01
A Ia Mints, I N Karaban', A A Litvinenko
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Abstract

The efficacy of sermion was studied in 41 patients of the middle and elderly ages. The reactive changes in the parameters of the cerebral circulation (the frontomastoidal RhEG), total hemodynamics, frequency-integration characteristics of EEG and visual evoked potentials at the administration of 2 mg and 4 mg of sermion were shown. There are given recommendations for the differential approach to the choice of the drug doses in the elderly persons taking into consideration the parameters of the background reactivity of the CNS and the state of vascular regulation.

[单次静脉注射血清对初始动脉粥样硬化性脑病患者脑循环和脑功能活动的影响]。
对41例中老年患者的临床疗效进行了观察。观察血清2 mg和4 mg给药时脑循环参数(额脑血管RhEG)、总血流动力学、脑电图频率积分特征和视觉诱发电位的反应性变化。考虑到中枢神经系统的背景反应性参数和血管调节状态,对老年人选择药物剂量的不同方法提出了建议。
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