{"title":"Escitalopram-induced hyperprolactinemic galactorrhea","authors":"Deepthi Yedla, V. Sharmila","doi":"10.4103/amjm.amjm_50_22","DOIUrl":null,"url":null,"abstract":"Galactorrhea is milky secretions from the breast in women who have not breast-fed for a year. Escitalopram, a selective serotonin reuptake inhibitor (SSRI), owing to its potency and tolerance, is regarded as the primary line drug in the management of depression and anxiety disorders. SSRIs may rarely cause symptoms brought on by enhanced prolactin levels. Antidepressants that increase serotonin may additionally cause a rise in prolactin by improving dopamine neurotransmission. In the current research, we present a case of hyperprolactinemic galactorrhea linked to escitalopram. A 32-year-old woman presented with bilateral breast heaviness and milky secretions after using escitalopram for anxiety and her serum prolactin level was found to be elevated. Galactorrhea disappeared and her prolactin level returned to normal after escitalopram was stopped.","PeriodicalId":138060,"journal":{"name":"Amrita Journal of Medicine","volume":"95 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Amrita Journal of Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/amjm.amjm_50_22","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Galactorrhea is milky secretions from the breast in women who have not breast-fed for a year. Escitalopram, a selective serotonin reuptake inhibitor (SSRI), owing to its potency and tolerance, is regarded as the primary line drug in the management of depression and anxiety disorders. SSRIs may rarely cause symptoms brought on by enhanced prolactin levels. Antidepressants that increase serotonin may additionally cause a rise in prolactin by improving dopamine neurotransmission. In the current research, we present a case of hyperprolactinemic galactorrhea linked to escitalopram. A 32-year-old woman presented with bilateral breast heaviness and milky secretions after using escitalopram for anxiety and her serum prolactin level was found to be elevated. Galactorrhea disappeared and her prolactin level returned to normal after escitalopram was stopped.