Morbidity and Mortality after Emergency and Urgent Colorectal Surgery for Malignant and Benign Disease

V. Ellensen, J. Elshove-Bolk, G. Baatrup
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引用次数: 2

Abstract

Aim: The aim of this study was to determine short and long-term morbidity and mortality rates after emergency colorectal surgery for benign and malignant disease in a high volume tertiary referral hospital in order to define factors predictive for outcome. Material and Methods: Characteristics and outcome of 196 consecutive emergency and 292 consecutive elective colorec- tal procedures were studied. A total of 91/196 emergency procedures were performed for malignant disease. The proce- dures reviewed included both palliative and curative procedures performed on an unselected patient population. Results were analysed by Cox regression and Kaplan-Meier analysis. Results: The total 30-day mortality for emergency and elective surgery was 20% and 3 % respectively, 36-month mortal- ity was 48% and 27%. The frequency of major or moderate complications after emergency procedures was 39%. The strongest predictors for 30 day mortality after emergency surgery were ASA score (Odds Ratio 2.5) and age (OR 1.5). Predictors for early postoperative complications were faecal contamination during surgery (OR 4.2) and ASA score (OR 2.0). The strongest predictor for 3 year mortality after emergency surgery was malignant disease (OR = 5.0). Other predic- tors for long-term outcome were procedures performed and degree of specialization of the surgeon. Conclusions: Short-term outcome is associated with patient and disease related factors, whereas long-term outcome is also correlated to the primary diseases, procedures performed and the degree of specialization of the surgeon. Decisions concerning the level of qualifications required for emergency procedures should be based upon patient and disease related factors as well as the procedure to be performed.
恶性和良性疾病急诊和紧急结直肠手术后的发病率和死亡率
目的:本研究的目的是确定在大容量三级转诊医院急诊结直肠良性和恶性疾病手术后的短期和长期发病率和死亡率,以确定预测预后的因素。材料与方法:对196例连续急诊和292例连续择期结肠手术的特点和结果进行了研究。共有91/196例恶性疾病急诊手术。审查的程序包括对未选择的患者群体进行的姑息治疗和治疗程序。结果采用Cox回归和Kaplan-Meier分析。结果:急诊和择期手术30天死亡率分别为20%和3%,36个月死亡率分别为48%和27%。急诊手术后出现严重或中度并发症的频率为39%。急诊手术后30天死亡率的最强预测因子是ASA评分(优势比2.5)和年龄(优势比1.5)。术后早期并发症的预测因子是术中粪便污染(OR 4.2)和ASA评分(OR 2.0)。急诊手术后3年死亡率的最强预测因子是恶性疾病(OR = 5.0)。其他长期预后的预测因素是手术过程和外科医生的专业化程度。结论:短期预后与患者和疾病相关因素有关,而长期预后也与原发疾病、实施的手术和外科医生的专业化程度有关。关于紧急程序所需资格水平的决定应根据与病人和疾病有关的因素以及要执行的程序。
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