Granulomatosis with Polyangiitis (Wegener’s) Masquerading as Non-Resolving Pneumonia

Ganesh Kalyanasundaram, Poh Yong Tan, Nilesh H Pawar, A. Taha
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Abstract

Non-resolving pneumonia (NRP) includes those cases of presumed pneumonia that progress, resolve slowly, or fail to achieve complete resolution despite appropriate treatment [1]. Granulomatosis with Polyangiitis (GPA), previously known as Wegener’s granulomatosis is a multi-system disorder characterized by systemic necrotizing vasculitis which most commonly affects the small and medium vessels of the upper and lower respiratory tract and the kidneys [2,3]. Diagnosis of GPA requires a high index of suspicion, as the initial presentation is usually nonspecific, and most patients are usually diagnosed around 3-12 months from the onset of symptoms [4]. We present a case of a patient with nonresolving pneumonia who was eventually diagnosed with GPA.
肉芽肿合并多血管炎(韦格纳氏),伪装成不能解决的肺炎
非消退性肺炎(Non-resolving pneumonia, NRP)包括进展缓慢、消退缓慢或经过适当治疗后仍无法完全消退的疑似肺炎病例[1]。多血管炎肉芽肿病(Granulomatosis with Polyangiitis, GPA),以前被称为Wegener肉芽肿病,是一种多系统疾病,以全身性坏死性血管炎为特征,最常见于上、下呼吸道和肾脏的中小血管[2,3]。GPA的诊断需要高度的怀疑指数,因为最初的表现通常是非特异性的,大多数患者通常在症状出现后3-12个月左右被诊断出来[4]。我们提出了一个病例的患者不解决肺炎谁最终被诊断为GPA。
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