The Role of Negative Pressure Wound Therapy with Instillation and Dwell Time in the Preparation of Wound Bed

Nishad Kerakad, R. Chittoria, S. Gupta, C. Reddy, P. Mohan, I. Pathan, S. Koliyath, N. Thomas
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Abstract

Introduction Although the negative pressure wound therapy (NPWT) is a time tested method of wound preparation, the role of NPWT with instillation and dwell time (NPWTi-d) in decreasing the downtime of wound preparation needs to be evaluated. Objective The objective of this study is assess the role of NPWTi-d in wound bed preparation. Materials and Methods This study was conducted in a tertiary care center, after getting informed consent and ethical clearance. NPWTi-d was done on a 36-years-old female with no known co-morbidities admitted with infected raw area over the right below knee amputation stump and exposed bone who was not responding well to conventional wound dressing. NPWT was applied with the help of sterile polyurethane sponge and two tubes. The antimicrobial solution used was ionic silver solution, just enough to wet the sponge completely and up to the point when the transparent occlusive covering begins to lift. Negative pressure was applied at 125 mmHg. The wound was bathed with ionic silver solution and it was allowed to stay in the wound for 10-minutes, after every 2-hours of negative pressure application. This was continued for 1-week. The dressing was opened at the end of 1-week, wound irrigated with normal saline, exudate swabs for culture taken and debrided, following which fresh NPWTi-d was applied. This was repeated for the next 3-weeks. Result By the end of third week, the wound became clean, fully covered with healthy granulation and the wound bed was ready to undergo the definitive wound cover procedure.
负压伤口滴注和停留时间在创面准备中的作用
虽然负压创面治疗(NPWT)是一种经过时间考验的创面准备方法,但具有滴注和停留时间的NPWT (NPWTi-d)在减少创面准备停机时间方面的作用需要进行评估。目的探讨NPWTi-d在伤口床制备中的作用。材料和方法本研究在获得知情同意和伦理许可后,在三级保健中心进行。NPWTi-d是对一名36岁女性进行的,她没有已知的合并症,入院时膝下右下截肢残端和暴露的骨头感染,对传统伤口敷料反应不佳。在无菌聚氨酯海绵和两根试管的帮助下应用NPWT。使用的抗菌溶液是离子银溶液,刚好足以完全湿润海绵,直到透明的闭塞覆盖物开始抬起。负压125 mmHg。用离子银溶液浸泡创面,每2小时负压一次,在创面内停留10分钟。持续1周。1周结束时打开敷料,用生理盐水冲洗创面,取分泌物拭子进行培养并清创,然后应用新鲜的NPWTi-d。在接下来的3周内重复这一实验。结果第三周结束时,创面清洁,健康肉芽覆盖,创面床准备进行最终创面覆盖。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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