Addressing Portal Hypertension: Exploring the Crucial Role of Partial Splenic Embolization in Critical Situations

Agnes Wanda Suwanto, Fini Amalia, A. Na
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Abstract

Background: Esophageal varices are one of the most common symptoms of direct outcomes of portal hypertension besides ascites, hepatorenal syndrome, and hypersplenism. Nonselective beta-blockers or band ligation are currently the effective primary preventive options for variceal hemorrhage. The use of partial splenic arterial embolization for the management of variceal hemorrhage in patients with portal hypertension has been described in a small number of reports. Case Report: A girl, 6 y.o., was hospitalized with hematemesis with hypovolemic shock. Laboratory findings show anemia and thrombocytopenia. Radiology and endoscopy show grade III esophageal varices with hepatosplenomegaly. Because of the high risk of morbidity in surgical procedures, partial splenic embolization was performed to treat portal hypertension. Discussion: The combination of varices and a low platelet count puts these patients at high risk for catastrophic hemorrhage. Partial splenic embolization reduces splenic blood volume, resulting in a decrease in venous drainage and a reduction in portal venous flow and pressure. Conclusion: The use of partial splenic arterial embolization to manage variceal hemorrhage in patients with portal hypertension has been described. Embolization can be used alone or in combination with other therapies, like endoscopic ligation or retrograde transvenous variceal obliteration, to treat a variety of conditions. Keywords: Embolization, esophageal varices, splenomegaly, portal hypertension
解决门静脉高压:探讨在危急情况下部分脾栓塞的关键作用
背景:除了腹水、肝肾综合征和脾功能亢进外,食管静脉曲张是门静脉高压症最常见的直接后果之一。非选择性受体阻滞剂或绑扎是目前有效的静脉曲张出血的初级预防选择。使用部分脾动脉栓塞治疗门静脉高压患者的静脉曲张出血已在少数报道中被描述。病例报告:1例6岁女童因呕血伴低血容量性休克住院。实验室结果显示贫血和血小板减少症。放射和内窥镜检查显示III级食管静脉曲张伴肝脾肿大。由于手术过程中发病率高,部分脾栓塞术被用于治疗门静脉高压症。讨论:静脉曲张和低血小板计数的结合使这些患者有发生灾难性出血的高风险。部分脾栓塞减少脾血容量,导致静脉引流减少,门静脉流量和压力降低。结论:应用部分脾动脉栓塞治疗门静脉高压患者的静脉曲张出血。栓塞可以单独使用或与其他疗法联合使用,如内窥镜结扎或逆行经静脉静脉曲张闭塞术,以治疗各种疾病。关键词:栓塞,食管静脉曲张,脾肿大,门脉高压
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