Effect of Pre-medication with Atropine on the Blood Pressure of Parturient Undergoing Caesarian Section under Spinal Anaesthesia

Orient Journal of Medicine Pub Date : 2004-05-18 DOI:10.4314/OJM.V15I1.29037

P. Nze

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引用次数: 4

Abstract

Objective: The effect of atropine given as a prophylactic intravenous bolus on the incidence and severity of hypotension was studied in 30 patients undergoing Caesarian section under spinal (subarachnoid) anaesthesia between January and September 1999. Method: Following the establishment of spinal anaesthesia, the patients were randomized to receive an immediate intravenous bolus of normal saline (Group A, n = 12) or 0.6mg of atropine sulphate (Group B, n = 18) in 2ml. Arterial blood pressure and heart rate were recorded every 3 minutes. The patients were asked to report any symptoms of nausea or fainting. Results: Both the incidence and severity of hypotension were reduced in the patients that had atropine prophylaxis (Group B) compared with the control group that received normal saline (Group A). The difference, however, did not reach statistical significance when tested with Chi-square statistic. Conclusion: In view of the improved maternal haemodynamic parameters, parturients undergoing Caesarian section under spinal anaesthesia may benefit from a prophylactic intravenous bolus of atropine. Key Words: Obstetric anaesthesia, Spinal Anaesthesia, Subarachnoid anaesthesia, Atropine prophylaxis. Orient Journal of Medicine Vol.15(1&2) 2003: 1-4

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预用药阿托品对脊柱麻醉下剖宫产产妇血压的影响

目的:观察1999年1 ~ 9月30例经脊髓(蛛网膜下腔)麻醉剖宫产术患者预防性静脉注射阿托品对低血压发生率及严重程度的影响。方法:脊髓麻醉建立后，患者随机接受生理盐水即刻静脉滴注(A组，n = 12)或硫酸阿托品0.6mg (B组，n = 18) 2ml。每3分钟记录一次动脉血压和心率。患者被要求报告任何恶心或晕厥的症状。结果:与给予生理盐水的对照组(A组)相比，给予阿托品预防治疗的患者(B组)低血压的发生率和严重程度均有所降低，但经卡方统计检验，差异无统计学意义。结论:鉴于产妇血流动力学参数的改善，脊髓麻醉下剖宫产时预防性静脉注射阿托品可能有益。关键词:产科麻醉，脊髓麻醉，蛛网膜下腔麻醉，阿托品预防东方医学杂志Vol.15(1&2) 2003: 1-4

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Orient Journal of Medicine

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