Herbal derived nanomedicines against for some human pathogens

Abstract

The aim of this study was to achieve the silver nanocrystals for therapeutic values. The Aristolochia bractiata leaves extract as a reducing substance for the biosynthesis of silver nanoparticles. UV-Vis spectra analysis, Dynamic Light Scattering Particle size analyzer, X-ray Diffraction method and Scanning electron microscopy (SEM) with X-ray spectroscopy (EDS) have been employed to characterize and confirmed the nanocrystal formation. In antimicrobial activity, the silver nanoparticles were most against some human pathogens. In bacteria, the test sample was most effective against Salmonella typhimurium NCIM 2501 (B5) while smaller effect was noticed from Micrococcus luteus NCIM 2871 (B4). In fungi, which was effective against Trichophyton rubrum MTCC 3272 (F4) whereas smaller effect was observed in Cryptococcus sp. MTCC 7076 (F2). All the microbial strains depict higher sensitivity to the higher concentration (30?L) for the test sample when compared to the positive control except few bacterial strains.