nsPEF characterization of a delivery device based on 1-mm Gap thin electrodes for the exposure of biological cells

Abstract

In this paper, an electromagnetic characterization of an electrode-based delivery system is proposed for the exposure of living biological cells to nanosecond pulses. The characterization of the 1-mm gap electrode device was carried out through experimental measurements and numerical simulations. The frequency time domain analyses demonstrate the adaptation of the proposed assembly up to 300 MHz. High voltage measurements and simulations were performed using an applied pulse duration of 10 ns and magnitude of 6.1 kV. This study proved the utility of this device for delivering pulses as short as 10 ns and achieving an electric field magnitude of 6 MV/m. This device can be used for real-time investigations of biological samples.