A Case of Idiopathic Pulmonary Fibrosis (IPF) Diagnosed with Progression Post-Covid-19 Pneumonia

T. Ozlu, A. Pehlivanlar
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Abstract

A chest tomography taken after COVID-19 revealed bilateral fibrotic foci areas, and two months later it was seen that they had been precursors to honeycomb lesions, and that the usual interstitial pneumonia (UIP) pattern associated with post-COVID pneumonia had occurred. It was noted that the fibrotic lesions in the left lung were already present before the disease. The lesions present in the patient, who had dyspnea pre-COVID-19 but had not been diagnosed with ILD, were considered to be UIP precursor lesions that progressed with the increase in fibroblast activity and the triggering of fibrotic pathways in the course of the disease. The patient was thus diagnosed with Idiopathic Pulmonary Fibrosis (IPF). We suggest that if a UIP appearance develops in COVID-19 patients with progressive fibrosis that is not relieved by anti-inflammatory treatments in long-term examinations, the possibility of IPF should be considered, and so the clinical and radiological findings of patients' pre-COVID-19 should be investigated for the early identification of IPF. Copyright © 2022 LookUs Scientific. All rights reserved.
1例特发性肺纤维化(IPF)诊断为covid -19后肺炎进展
新冠肺炎后的胸部断层扫描显示双侧纤维化灶区,两个月后发现它们是蜂窝状病变的前兆,并出现了与新冠肺炎相关的常见间质性肺炎(UIP)模式。注意到左肺的纤维化病变在发病前就已经存在。患者在covid -19前有呼吸困难,但未被诊断为ILD,该病变被认为是UIP前体病变,随着成纤维细胞活性的增加和疾病过程中纤维化途径的触发而进展。因此,患者被诊断为特发性肺纤维化(IPF)。我们建议,如果在COVID-19进行性纤维化患者中出现UIP外观,且长期检查抗炎治疗未缓解,应考虑IPF的可能性,因此应调查患者COVID-19前的临床和影像学表现,以早期识别IPF。版权所有©2022 LookUs Scientific。版权所有。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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