Antibiotic prescribing patterns in a neonatal intensive care unit

N. Schellack, A. Gous
{"title":"Antibiotic prescribing patterns in a neonatal intensive care unit","authors":"N. Schellack, A. Gous","doi":"10.1080/10158782.2011.11441465","DOIUrl":null,"url":null,"abstract":"An outbreak of invasive candidiasis in the neonatal intensive care unit (NICU) of the Dr George Mukhari Academic Hospital in Ga-Rankuwa necessitated evaluation of the antibiotic prescribing practices in the unit. A selective randomised sample of 100 patients was followed up over a nine-month period to evaluate prescribing patterns. The existing antibiotic policy was used to compare the prescription practices and use of antibiotics. The frequency of use, number of antibiotics per patient and duration of use were documented. Of the 100 patients followed, 95 were prescribed intravenous antibiotics. All prescribed antibiotics for 77 patients are listed in the antibiotic policy. Nineteen different antibiotics were prescribed, and 11 of the 19 prescribed antibiotics appear in the antibiotic policy. Most patients received more than two antibiotics during their stay, as the average number of antibiotics used per patient during the study period was 3.4. The average duration of use for all antibiotics, except cefepime and ceftriaxone, was for longer than seven days. Although antibiotics were used according to the ward protocol in the majority of patients, deviations from the protocol were associated with patients’ clinical condition and/or results from blood cultures. The duration of antibiotic use needs to be monitored to prevent unnecessary prolonged use, as in this investigation. An antibiotic policy may be useful to guide and measure rational antibiotic therapy in a NICU.","PeriodicalId":335691,"journal":{"name":"The Southern African Journal of Epidemiology and infection","volume":"26 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2011-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"10","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Southern African Journal of Epidemiology and infection","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/10158782.2011.11441465","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 10

Abstract

An outbreak of invasive candidiasis in the neonatal intensive care unit (NICU) of the Dr George Mukhari Academic Hospital in Ga-Rankuwa necessitated evaluation of the antibiotic prescribing practices in the unit. A selective randomised sample of 100 patients was followed up over a nine-month period to evaluate prescribing patterns. The existing antibiotic policy was used to compare the prescription practices and use of antibiotics. The frequency of use, number of antibiotics per patient and duration of use were documented. Of the 100 patients followed, 95 were prescribed intravenous antibiotics. All prescribed antibiotics for 77 patients are listed in the antibiotic policy. Nineteen different antibiotics were prescribed, and 11 of the 19 prescribed antibiotics appear in the antibiotic policy. Most patients received more than two antibiotics during their stay, as the average number of antibiotics used per patient during the study period was 3.4. The average duration of use for all antibiotics, except cefepime and ceftriaxone, was for longer than seven days. Although antibiotics were used according to the ward protocol in the majority of patients, deviations from the protocol were associated with patients’ clinical condition and/or results from blood cultures. The duration of antibiotic use needs to be monitored to prevent unnecessary prolonged use, as in this investigation. An antibiotic policy may be useful to guide and measure rational antibiotic therapy in a NICU.
新生儿重症监护病房的抗生素处方模式
Ga-Rankuwa Dr George Mukhari学术医院新生儿重症监护病房(NICU)爆发侵袭性念珠菌病,有必要对该病房的抗生素处方做法进行评估。对100名患者的随机抽样进行了为期9个月的随访,以评估处方模式。采用现有的抗生素政策对抗生素的处方做法和使用情况进行比较。记录使用频率、每位患者的抗生素数量和使用时间。在随访的100名患者中,95名患者接受了静脉注射抗生素。77名患者的所有处方抗生素都列在抗生素政策中。开出了19种不同的抗生素,其中11种抗生素出现在抗生素政策中。大多数患者在住院期间使用了两种以上的抗生素,因为在研究期间每位患者平均使用了3.4种抗生素。除头孢吡肟和头孢曲松外,所有抗生素的平均使用时间均超过7天。尽管大多数患者根据病房方案使用抗生素,但与方案的偏差与患者的临床状况和/或血培养结果有关。需要监测抗生素使用的持续时间,以防止不必要的长时间使用,如本调查所示。抗生素政策可能有助于指导和衡量新生儿重症监护病房的合理抗生素治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信