Effectiveness of Early Intervention by Specialized Institutions for Liver Cirrhosis Patients

T. Hisanaga, T. Yamasaki, M. Maeda, T. Iwamoto, I. Saeki, Toshihiko Matsumoto, I. Hidaka, Yoshio Marumoto, T. Ishikawa, T. Takami, I. Sakaida
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Abstract

This study examines liver cirrhosis ( LC ) patients’ backgrounds and clinical courses to clarify the effectiveness of specialized institutional intervention. The early intervention group, examined prior to symptom manifestation, had a higher proportion of cases caused by HCV, and the purpose of the examination was to investigate abnormalities in liver function and the extent of pre‑existing cirrhosis. Otherwise, the late intervention group, examined after symptom manifestation, had a higher proportion of cases caused by alcohol, and often patients only sought medical care after experiencing gastrointestinal variceal bleeding or other symptoms. The early group’s Child‑Pugh scores remained low over long periods and lived for long durations without incident. The late group, by contrast, had high scores and only showed short‑term improvement. Specialized intervention in cases of LC is effective, but must take place early on to improve the prognosis. Also, promoting patient referrals and coordinated medical care continue to be important.
专业机构对肝硬化患者早期干预的效果分析
本研究考察肝硬化(LC)患者的背景和临床过程,以阐明专业机构干预的有效性。早期干预组在症状出现之前进行检查,HCV引起的病例比例更高,检查的目的是调查肝功能异常和已存在的肝硬化程度。否则,在症状出现后进行检查的晚期干预组,由酒精引起的病例比例更高,而且患者往往在出现胃肠道静脉曲张出血或其他症状后才去就医。早期组的Child - Pugh得分在很长一段时间内保持较低水平,并且在很长一段时间内没有发生任何事故。相比之下,晚睡的那一组得分很高,而且只显示出短期的改善。在LC病例中,专门干预是有效的,但必须尽早进行以改善预后。此外,促进病人转诊和协调医疗护理仍然很重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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