The Importance of Molecular Diagnostics and Screening Programs in Monitoring and Evaluation of Colorectal Cancer in the Republic of North Macedonia

Jovanka Trpkovska, N. Velickova
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引用次数: 1

Abstract

Colorectal cancer (CRC) is one of the most common malignant diseases (12 % of the total) that occurs with an incidence of 15 – 30 new cases per 100,000 population per year in European Union countries. The risk of this disease during life depends on many factors such as age, diet, physical activity, personal and family predisposition. Several preventive measures can reduce the number of colorectal cancer patients. First of all, the regular screening which allows the detection of precancerous polyps or cancer in the early stage and their successful surgical removal. The purpose of this paper is to highlight the importance of screening programs as a preventive measure for the early detection of colorectal cancer and to reduce the morbidity and mortality of this disease. The strategy for improving the early detection of colorectal cancer also implies availability of useful information about the importance of screening programs for everyone as well as educating health care staff about the program itself. Number of newly registered colorectal cancer cases in 2009 in the Republic North Macedonia stands at 547 with a rate of 26.7 compared to 2018 with 839 newly registered cases with a rate of 40.4 which clearly indicates an increasing trend of colorectal cancer. Multidisciplinary approach to early detection of colorectal cancer, continuity of Program funding and quality of services will lead to reduction of morbidity and mortality of this type of cancer.
北马其顿共和国分子诊断和筛查项目在大肠癌监测和评估中的重要性
结直肠癌(CRC)是最常见的恶性疾病之一(占总数的12%),在欧洲联盟国家,每年每10万人中有15 - 30例新发病例。一生中患这种疾病的风险取决于许多因素,如年龄、饮食、身体活动、个人和家庭易感性。几种预防措施可以减少结直肠癌患者的数量。首先,定期筛查可以在早期发现癌前息肉或癌症并成功进行手术切除。本文的目的是强调筛查计划作为早期发现结直肠癌的预防措施的重要性,并降低这种疾病的发病率和死亡率。提高结肠直肠癌早期检测的策略还意味着提供有关筛查项目对每个人的重要性的有用信息,以及对卫生保健人员进行项目本身的教育。北马其顿共和国2009年新登记的结直肠癌病例数为547例,发病率为26.7,而2018年新登记的病例数为839例,发病率为40.4,这清楚地表明结直肠癌呈上升趋势。早期发现结直肠癌的多学科方法,项目资金的连续性和服务质量将导致降低这类癌症的发病率和死亡率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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