H. A. Ahmed, P. Mahanta, D. Bhattacharyya, J. Kalita
{"title":"GERC: Tree Based Clustering for Gene Expression Data","authors":"H. A. Ahmed, P. Mahanta, D. Bhattacharyya, J. Kalita","doi":"10.1109/BIBE.2011.54","DOIUrl":null,"url":null,"abstract":"Measurement of gene expression using DNA micro arrays have revolutionized biological and medical research. This paper presents a divisive clustering algorithm that produces a tree of genes called GERC tree along with the generated clusters. Unlike a dendrogram, a GERC tree is a general tree and it is an ample resource for biological information about the genes in a data set. The leaves of the tree represent the desired clusters. The clustering method was tested with several real-life data sets and the proposed method has been found satisfactory.","PeriodicalId":391184,"journal":{"name":"2011 IEEE 11th International Conference on Bioinformatics and Bioengineering","volume":"1 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2011-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"16","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"2011 IEEE 11th International Conference on Bioinformatics and Bioengineering","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/BIBE.2011.54","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 16
Abstract
Measurement of gene expression using DNA micro arrays have revolutionized biological and medical research. This paper presents a divisive clustering algorithm that produces a tree of genes called GERC tree along with the generated clusters. Unlike a dendrogram, a GERC tree is a general tree and it is an ample resource for biological information about the genes in a data set. The leaves of the tree represent the desired clusters. The clustering method was tested with several real-life data sets and the proposed method has been found satisfactory.